Glucose and insulin levels in female (F; (A,C,E)) and male (M; (B,D,F)) mice during double crossover. Fed glucose (A,B) was measured at 11.30 am when mice were postprandial. Fasting glucose (C,D) and fasting insulin (E,F) were measured following an overnight fast. Data represent means ± SEM from N = 6 to 10 mice/group. Asterisks denote significant differences between groups (*P <0.05; **P <0.001), assessed using one-way analysis of variance (ANOVA).