Body weight curves and glucose tolerance test. (A) Body weight curves (means ± S.E.M.) during the length of the study (*P< 0.05,DIO> DR and CD). The glucose tolerance test (GTT) was performed (B) at 8 months (*P< 0.05, DIO and DR > CD; #P< 0.05, DIO > DR and CD) and (C) 15 months after diet introduction (*P< 0.05, DIO > DR and CD; CD, n =12; high saturated fat and low carbohydratediet: DIO, n = 7; DR, n = 6). Blood glucose levels (means ± S.E.M.) were assessed at fasting (0 minutes), 30, 60 and 120 minutes after an intraperitoneal glucose injection. Insert: area under the curve (AUC) of the GTT.CD, control diet; DIO, diet-induced obese; DR, diet resistant.