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Table 2 Real-time PCR assessment of myosin heavy chain (MHC) isoform specific mRNAs of MHC I, MHC IIa, MHC IIx and MHC IIb

From: Evidence of changes to skeletal muscle contractile properties during the initiation of disease in the ageing guinea pig model of osteoarthritis

Parameter 2mo 3mo 5mo 7mo Pvalue
MHC I mRNA 0.195 ± 0.052 0.566 ± 0.362 0.034 ± 0.011 0.342 ± 0.300 0.117
MHC IIa mRNA 0.051 ± 0.008 0.077 ± 0.016 0.055 ± 0.023 0.051 ± 0.009 0.627
MHC IIx mRNA 0.165 ± 0.041 0.584 ± 0.191 0.184 ± 0.094 0.237 ± 0.050 0.038
MHC IIb mRNA 0.088 ± 0.015 0.084 ± 0.019 0.061 ± 0.024 0.051 ± 0.009 0.417
  1. Data are mean expression units ± SEM normalised to total first strand cDNA concentration; n = 6.