Longevity & Healthspan

Table 2 Real-time PCR assessment of myosin heavy chain (MHC) isoform specific mRNAs of MHC I, MHC IIa, MHC IIx and MHC IIb

From: Evidence of changes to skeletal muscle contractile properties during the initiation of disease in the ageing guinea pig model of osteoarthritis

Parameter	2mo	3mo	5mo	7mo	Pvalue
MHC I mRNA	0.195 ± 0.052	0.566 ± 0.362	0.034 ± 0.011	0.342 ± 0.300	0.117
MHC IIa mRNA	0.051 ± 0.008	0.077 ± 0.016	0.055 ± 0.023	0.051 ± 0.009	0.627
MHC IIx mRNA	0.165 ± 0.041	0.584 ± 0.191	0.184 ± 0.094	0.237 ± 0.050	0.038
MHC IIb mRNA	0.088 ± 0.015	0.084 ± 0.019	0.061 ± 0.024	0.051 ± 0.009	0.417

Data are mean expression units ± SEM normalised to total first strand cDNA concentration; n = 6.

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