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Figure 3 | Longevity & Healthspan

Figure 3

From: Evidence of changes to skeletal muscle contractile properties during the initiation of disease in the ageing guinea pig model of osteoarthritis

Figure 3

Real-time PCR assessment of myosin heavy chain 1 (MHC IIX) isoform specific mRNA. (A) MHC IIX mRNA expression in the quadriceps muscle of guinea pigs aged between 2 and 7 months. Data are mean expression units + SEM normalised to total first strand cDNA concentration; n = 6; * denotes P <0.05. (B) Linear regression analysis depicting the relationship between MHC IIX mRNA expression (y-axis) and total histological grade (x-axis) in guinea pigs at 3 months of age; n = 6. (C) Linear regression analysis depicting the relationship between MHC IIX mRNA expression (y-axis) and total histological grade (x-axis) in guinea pigs aged between 2 and 7 months; N = 24.

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